Ethyl Bromide → Diethyl 3-Bromobenzylphosphonate

HRID 4910

Reaction equation

HRID 4910 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5]Br.[P:10]([O:17]CC)([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13].C(Br)C>>[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][P:10](=[O:17])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13]

Participants

4

Reactant 3

HCID 6332Ethyl BromideHCID 31215Triethyl phosphiteHCID 699793-Bromobenzyl bromide

Product 1

HCID 10979718Diethyl 3-Bromobenzylphosphonate

Procedure

50 g (0.2 mol) of 3-bromobenzyl bromide and 33.2 g (0.2 mol) of triethyl phosphite were heated at 140° C. for 2 hours, during which ethyl bromide was distilled off. The product was distilled over a 30 cm Vigreux column.

Workup

  1. distillationwas distilled off
  2. distillationThe product was distilled over a 30 cm Vigreux column

Sources & evidence

ORD record
ord-5f68bfe24502413aa07932d4095cc464
Source dataset
uspto-grants-1993_09
Patent number
US05242908

Linked notes

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