Tetrahydrothiophene → 1-(3,3-Dimethyl-2-oxobutyl)thiolan-1-ium bromide

HRID 492266

Reaction equation

HRID 492266 reaction equation
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:6][CH2:7][C:8](=[O:13])[C:9]([CH3:12])([CH3:11])[CH3:10]>CC(C)=O>[Br-:6].[CH3:10][C:9]([CH3:12])([CH3:11])[C:8](=[O:13])[CH2:7][S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 1127TetrahydrothiopheneHCID 21642Bromopinacolone

Product 1

HCID 225645781-(3,3-Dimethyl-2-oxobutyl)thiolan-1-ium bromide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

70.2 Parts of tetrahydrothiophene was dissolved in 750 parts of acetone, and 150 parts of 1-bromo-3,3-dimethyl-2-butanone was added dropwise thereto. After the mixture was stirred at room temperature for 24 hours, white solid obtained was filtered, washed with acetone and dried to obtain 161.3 parts of 1-(3,3-dimethyl-2-oxobutyl)tetrahydrothiophenium bromide in the form of white crystals.

Workup

  1. additionwas added dropwise
  2. customwhite solid obtained
  3. filtrationwas filtered
  4. washwashed with acetone
  5. customdried

Sources & evidence

ORD record
ord-4efe8ae645ce4c51b6e4a7eaecb65e22
Source dataset
uspto-grants-2009_05
Patent number
US07531686B2

Linked notes

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