Tributylphosphine → 4-(4-Chloro-2-fluorophenoxy)-7-(3-(1,1-dioxothiomorpholino)propoxy)-6-methoxyquinazoline
Reaction equation
[O:1]=[S:2]1(=[O:12])[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][OH:11])[CH2:4][CH2:3]1.N(C(N1CCCCC1)=O)=NC(N1CCCCC1)=O.[Cl:31][C:32]1[CH:51]=[CH:50][C:35]([O:36][C:37]2[C:46]3[C:41](=[CH:42][C:43](O)=[C:44]([O:47][CH3:48])[CH:45]=3)[N:40]=[CH:39][N:38]=2)=[C:34]([F:52])[CH:33]=1.C(P(CCCC)CCCC)CCC>C(OCC)C.C(Cl)Cl>[Cl:31][C:32]1[CH:51]=[CH:50][C:35]([O:36][C:37]2[C:46]3[C:41](=[CH:42][C:43]([O:11][CH2:10][CH2:9][CH2:8][N:5]4[CH2:6][CH2:7][S:2](=[O:1])(=[O:12])[CH2:3][CH2:4]4)=[C:44]([O:47][CH3:48])[CH:45]=3)[N:40]=[CH:39][N:38]=2)=[C:34]([F:52])[CH:33]=1Participants
7
