Stannous chloride dihydrate → HCID 69489430, compound

Reaction equation

[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([Cl:14])[C:11]([CH3:15])=[CH:10][C:9]=1[N+:16]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([Cl:14])[C:11]([CH3:15])=[CH:10][C:9]=1[NH2:16])([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 61436Stannous chloride dihydrate

HCID 69486680(5-Chloro-4-methyl-2-nitro-phenyl)-carbamic acid tert-butyl ester

Product 1

HCID 69489430HCID 69489430, compound

Procedure

(2-Amino-5-chloro-4-methyl-phenyl)-carbamic acid tert-butyl ester was prepared from (5-chloro-4-methyl-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A16) (11.9 g, 41.4 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a yellow solid (9.25 g, 87%).

Sources & evidence

ORD record: ord-40982624714c45139eb27aefd262491a
Source dataset: uspto-grants-2005_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06949542B2

Reaction notes

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