HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester → Carbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester | HCID 69489589 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Carbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl ester | HCID 69489489 | — |
Reaction Steps
The title compound was prepared from (2-nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester (Example A22) (10.38 g, 32.2 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light brown solid (8.76 g, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-2fac2924806b4032976ad77bf9f8f930 |
| Source note | uspto-grants-2005_09 |