Hydrochloric Acid → Ethyl 2-(4-(bromomethyl)phenyl)acetate

Reaction equation

[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1.Cl.[CH2:14](O)[CH3:15]>>[Br:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][C:10]([O:12][CH2:14][CH3:15])=[O:11])=[CH:7][CH:8]=1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 45190564-(Bromomethyl)phenylacetic acid

Product 1

HCID 15712209Ethyl 2-(4-(bromomethyl)phenyl)acetate

Procedure

1.00 g of 2-[4-(bromomethyl)phenyl]acetic acid was suspended in 5 mL of a 4M solution of hydrogen chloride in ethanol, and this suspension was stirred for 2 hours at room temperature. The reaction mixture was concentrated under reduced pressure to yield 0.954 g of ethyl 2-[4-(bromomethyl)phenyl]acetate as light brown oil.