Water → HCID 86624085, compound

HRID 512456

Reaction equation

HRID 512456 reaction equation
[F:1][C:2]([F:10])([C:6]([F:9])([F:8])[F:7])[C:3](Cl)=[O:4].N1C=CC=CC=1.[CH:17]([O:19][CH2:20][CH2:21][CH2:22][CH3:23])=[CH2:18].O>ClCCl>[CH2:20]([O:19][CH:17]=[CH:18][C:3](=[O:4])[C:2]([F:10])([F:1])[C:6]([F:9])([F:8])[F:7])[CH2:21][CH2:22][CH3:23]

Participants

6

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 8108Butyl vinyl etherHCID 67911Perfluoropropionyl chloride

Product 1

HCID 86624085HCID 86624085, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Conditions

Temperature
-10 °C

Procedure

With stirring at −10° C., 17.0 g (93.2 mmol) of pentafluoropropionyl chloride—dissolved in 20 ml of dichloromethane—were added to a mixture of 8.11 g (102 mmol) pyridine and 9.33 g (93.2 mmol) of butyl vinyl ether in 200 ml of dichloromethane. After the addition, stirring was continued at room temperature for a further 15 h. 200 ml of water were then added to the mixture, and the organic phase was separated off, dried and concentrated. This gave 18.9 g (82% of theory) of a yellowish oil.

Workup

  1. additionAfter the addition
  2. stirringstirring
  3. customthe organic phase was separated off
  4. customdried
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-aa141b5811d04a5db4f0e3b86a915386
Source dataset
uspto-grants-2015_08
Patent number
US09102623B2

Linked notes

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