Cesium carbonate → Ethyl 5-(4-fluorobenzamido)-2-[methyl(quinolin-6-yl)amino]thiazole-4-carboxylate
Reaction equation
Br[C:2]1[S:3][C:4]([NH:12][C:13](=[O:21])[C:14]2[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=2)=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[N:6]=1.CC1(C)C2C(=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=CC=2)OC2C(P(C3C=CC=CC=3)C3C=CC=CC=3)=CC=CC1=2.C(=O)([O-])[O-].[Cs+].[Cs+].[CH3:70][NH:71][C:72]1[CH:73]=[C:74]2[C:79](=[CH:80][CH:81]=1)[N:78]=[CH:77][CH:76]=[CH:75]2>C1(C)C=CC=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[F:20][C:17]1[CH:18]=[CH:19][C:14]([C:13]([NH:12][C:4]2[S:3][C:2]([N:71]([CH3:70])[C:72]3[CH:73]=[C:74]4[C:79](=[CH:80][CH:81]=3)[N:78]=[CH:77][CH:76]=[CH:75]4)=[N:6][C:5]=2[C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:21])=[CH:15][CH:16]=1Participants
7
