Potassium Cyanide → 5-((2R,4S)-4-cyano-2-(3-fluorophenyl)pyrrolidin-1-yl)-N,N-bis(4-methoxybenzyl)pyrazolo[1,5-a]pyridine-3-carboxamide
Reaction equation
CS(O[C@@H:6]1[CH2:10][C@H:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[CH:12]=2)[N:8]([C:18]2[CH:23]=[CH:22][N:21]3[N:24]=[CH:25][C:26]([C:27](=[O:47])[N:28]([CH2:38][C:39]4[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[CH:41][CH:40]=4)[CH2:29][C:30]4[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][CH:31]=4)=[C:20]3[CH:19]=2)[CH2:7]1)(=O)=O.[C-:48]#[N:49].[K+]>CS(C)=O>[C:48]([C@@H:6]1[CH2:7][N:8]([C:18]2[CH:23]=[CH:22][N:21]3[N:24]=[CH:25][C:26]([C:27]([N:28]([CH2:29][C:30]4[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][CH:31]=4)[CH2:38][C:39]4[CH:40]=[CH:41][C:42]([O:45][CH3:46])=[CH:43][CH:44]=4)=[O:47])=[C:20]3[CH:19]=2)[C@@H:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[CH:12]=2)[CH2:10]1)#[N:49]Participants
4
Conditions
- Temperature
- 90 °C