Stannous Chloride → HCID 68183213, compound
Reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([NH:12][C:13]2[CH:14]=[CH:15][CH:16]=[C:17]3[C:22]=2[N:21]=[CH:20][CH:19]=[CH:18]3)(=[O:11])=[O:10])=[C:5]([N+:23]([O-])=O)[CH:4]=1)#[N:2].Cl[Sn]Cl>Cl.CCO>[NH2:23][C:5]1[CH:4]=[C:3]([C:1]#[N:2])[CH:8]=[CH:7][C:6]=1[S:9]([NH:12][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]2[C:22]=1[N:21]=[CH:20][CH:19]=[CH:18]2)(=[O:11])=[O:10]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
In a similar fashion using route 1 general procedure 4, 4-cyano-2-nitro-N-quinolin-8-yl-benzenesulfonamide (Intermediate 250) (0.63 g, 1.77 mmol), SnCl2 (2.0 g, 10.6 mmol), conc.HCl (5 drops) and EtOH (15 ml) gave the title compound (0.36 g, 61%) which was used in the next step without further purification.