Hydrazine hydrate (1:1) → (4-chloro-phenyl)-[9-(2-ethoxyethyl)-2-hydrazino-9H-purin-6-yl]-amine

HRID 524523

Reaction equation

HRID 524523 reaction equation
Cl[C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH2:11][CH2:12][O:13][CH2:14][CH3:15])=[C:4]([NH:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)[N:3]=1.O.[NH2:25][NH2:26]>>[Cl:23][C:20]1[CH:21]=[CH:22][C:17]([NH:16][C:4]2[N:3]=[C:2]([NH:25][NH2:26])[N:10]=[C:9]3[C:5]=2[N:6]=[CH:7][N:8]3[CH2:11][CH2:12][O:13][CH2:14][CH3:15])=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 59322264[2-Chloro-9-(2-ethoxy-ethyl)-9H-purin-6-yl]-(4-chloro-phenyl)-amine

Product 1

HCID 59322260(4-chloro-phenyl)-[9-(2-ethoxyethyl)-2-hydrazino-9H-purin-6-yl]-amine

Procedure

Was prepared according to Example 8 from [2-chloro-9-(2-ethoxy-ethyl)-9H-purin-6-yl]-(4-chloro-phenyl)-amine and hydrazine monohydrate.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-8413e028acbe4c01be32335172e90238
Source dataset
uspto-grants-2016_05
Patent number
US09340544B2

Linked notes

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