Hydrochloric Acid → Hydrochloric Acid
Reaction equation
[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH:7]([NH:11]C(=O)OC(C)(C)C)[CH2:6]1.[ClH:23]>O1CCOCC1>[ClH:23].[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH:7]([NH2:11])[CH2:6]1Participants
5
Reactant 2
Product 2
Reagents, catalysts & solvents 1
Procedure
tert-Butyl 3-(2-fluorophenoxy)cyclohexylcarbamate was stirred in a solution of HCl in dioxane (4 M) at room temperature for overnight. The product, HCl salt of 3-(2-fluorophenoxy)cyclohexanamine, was obtained after removal of solvent.
Sources & evidence
- ORD record
- ord-d6d3852e758f4248aba2bfcad9e3c507
- Source dataset
- uspto-grants-2016_05
- Patent number
- US09351965B2
Reaction notes
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