Toluene → 2-Methyl-4-{(E)-2-[5-(3-trifluoromethyl phenyl)pyridin-2-yl]vinyl}octahydropyrrolo[3,4-a]indolizine-1,3-dione

Reaction equation

Br[C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[CH:10]2[N:18]3[CH:13]([CH2:14][CH2:15][CH2:16][CH2:17]3)[CH:12]3[C:19](=[O:24])[N:20]([CH3:23])[C:21](=[O:22])[CH:11]23)=[N:6][CH:7]=1.[F:25][C:26]([F:37])([F:36])[C:27]1[CH:28]=[C:29](B(O)O)[CH:30]=[CH:31][CH:32]=1.C(=O)([O-])[O-].[K+].[K+].C1(C)C=CC=CC=1>O.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C(O)C>[CH3:23][N:20]1[C:21](=[O:22])[CH:11]2[CH:10](/[CH:9]=[CH:8]/[C:5]3[CH:4]=[CH:3][C:2]([C:31]4[CH:30]=[CH:29][CH:28]=[C:27]([C:26]([F:37])([F:36])[F:25])[CH:32]=4)=[CH:7][N:6]=3)[N:18]3[CH:13]([CH:12]2[C:19]1=[O:24])[CH2:14][CH2:15][CH2:16][CH2:17]3