4-Phenyl-2-butanol → 4-Methoxybenzyl alcohol

HRID 541177

Reaction equation

HRID 541177 reaction equation
O[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6]N=1)[CH3:3].C1(CC[CH:18]([OH:20])C)C=CC=CC=1.C1C2C3[NH+]([O-:30])C(C2)CC1C3>>[CH3:18][O:20][C:4]1[CH:9]=[CH:8][C:7]([CH2:6][OH:30])=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 613024-Phenyl-2-butanolHCID 86784alpha-Methyl-2-pyridinemethanolHCID 1015366402-Oxido-2-azoniatricyclo[3.3.1.03,7]nonane

Product 1

HCID 77384-Methoxybenzyl alcohol

Procedure

2-(1-Hydroxyethyl)pyridine (76.8 mg, 0.624 mmol) was oxidized in the same manner as that described in Example 8, (a) (except that Nor-AZADO was used at 3 mol %, and the reaction was performed at room temperature) to obtain the objective compound (66.0 mg; yield, 87.4%). The spectrum data were found to be the same as those obtained in Example 6, (h).

Workup

  1. customwas performed at room temperature
  2. customto obtain
  3. customthe objective compound (66.0 mg; yield, 87.4%)

Sources & evidence

ORD record
ord-31220d8df9174332927d5f16647c901d
Source dataset
uspto-grants-2014_10
Patent number
US08871981B2

Linked notes

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