Furfurylamine → HCID 178469827, compound

HRID 543658

Reaction equation

HRID 543658 reaction equation
CS[C:3]1[N:8]=[C:7]([OH:9])[C:6]([C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:5][N:4]=1.[CH2:15]([NH2:21])[C:16]1[O:20][CH:19]=[CH:18][CH:17]=1>C(O)CCC>[CH2:15]([NH:21][C:3]1[N:8]=[C:7]([OH:9])[C:6]([C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:5][N:4]=1)[C:16]1[O:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 3438FurfurylamineHCID 178418871HCID 178418871, compound

Product 1

HCID 178469827HCID 178469827, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

2-Methylthio-5-ethoxycarbonyl-4-hydroxypyrimidine (535 mg, 2.5 mmol) was refluxed in butanol overnight with furfurylamine (335 μl, 3.8 mmol). The named product crystallized out and was filtered off (577 mg, 88%).

Workup

  1. customThe named product crystallized out and
  2. filtrationwas filtered off (577 mg, 88%)

Sources & evidence

ORD record
ord-5fc38c36f3374f8f856ad7b712772c76
Source dataset
uspto-grants-1984_05
Patent number
US04447422

Linked notes

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