Ethanethioic acid cis-(+/-)-S-[5-(Azidomethyl)tetrahydro-3-furanyl]ester → cis-(+/-)-5-(Azidomethyl)tetrahydro-3-furanthiol

HRID 54779

Reaction equation

HRID 54779 reaction equation
[N:1]([CH2:4][C@H:5]1[O:9][CH2:8][C@@H:7]([S:10]C(=O)C)[CH2:6]1)=[N+:2]=[N-:3]>O1CCCC1.C[O-].[Na+].CO>[N:1]([CH2:4][C@H:5]1[O:9][CH2:8][C@@H:7]([SH:10])[CH2:6]1)=[N+:2]=[N-:3]

Participants

4

Reactant 1

HCID 86750331Ethanethioic acid cis-(+/-)-S-[5-(Azidomethyl)tetrahydro-3-furanyl]ester

Product 1

HCID 86750332cis-(+/-)-5-(Azidomethyl)tetrahydro-3-furanthiolYield 64.8%

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 23694274Sodium methanolate methanolSolvent

Procedure

The title compound is prepared by the procedure of Example 16 using 0.310 g of product from Example 61 in 4.5 ml of tetrahydrofuran and 0.30 ml of sodium methoxide/methyl alcohol to give 0.159 g of the desired product.

Sources & evidence

ORD record
ord-6d5cb41560274ce28dc5b3f7aa3ce5be
Source dataset
uspto-grants-1997_04
Patent number
US05623081

Linked notes

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