Phthalazine → 3,4-Dihydro-3-methyl-1-phenylbenzo[f]phthalazine

HRID 54973

Reaction equation

[C:1]([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][C:10]=1[CH3:19])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:20]1C2C(=CC=CC=2)C=[N:22][N:21]=1>>[CH3:20][N:21]1[N:22]=[C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:9]2[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[CH:12]=[CH:11][C:10]=2[CH2:19]1

Participants

Reactant 2

HCID 9207Phthalazine

HCID 111609401-Benzoyl-2-methylnaphthalene

Product 1

HCID 150508823,4-Dihydro-3-methyl-1-phenylbenzo[f]phthalazine

Procedure

By the procedure described in Example 189, 4.4 g (18 mmol) of the benzoylnaphthalene was converted to 1.73 g of the phthalazine product, which was reduced immediately as shown in Table G.

Sources & evidence

ORD record: ord-18f0ac08d4ae43d1a812e50fd0c7447a
Source dataset: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05624922

Linked notes

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