Hydrochloric Acid → Methyl 5-hexenimidoate hydrochloride
Reaction equation
[C:1](#[N:7])[CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6].[CH3:8][OH:9].[ClH:10]>CCOCC>[ClH:10].[C:1](=[NH:7])([O:9][CH3:8])[CH2:2][CH2:3][CH2:4][CH:5]=[CH2:6]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Through a stirred solution of 5-hexenenitrile (3 g, 31Mmol) and MeOH (35 mmol) in Et2O (30 ml), at 0° C., HCl gas was bubbled for 10 minutes. Solvent was evaporated in vacuo and the residue treated with Et2O to give 5.1 g of the title compound as white solid, which was used without further purification.
Workup
- customSolvent was evaporated in vacuo
- additionthe residue treated with Et2O
Sources & evidence
- ORD record
- ord-2faf6c8cb40842379980e322da0024ce
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07947683B2
Reaction notes
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