Hydrazine hydrate (1:1) → 2,2-Dimethyl-4-pentenohydrazide
Reaction equation
[CH3:1][C:2]([CH3:10])([CH2:7][CH:8]=[CH2:9])[C:3](OC)=[O:4].O.[NH2:12][NH2:13]>CO>[CH3:1][C:2]([CH3:10])([CH2:7][CH:8]=[CH2:9])[C:3]([NH:12][NH2:13])=[O:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 60 °C
Procedure
To a solution of methyl 2,2-dimethyl-4-pentenoate (1 g) in MeOH (2 ml) was added hydrazine monohydrate (2.7 ml). The solution was heated in a close microwave vial at 60° C. for 12 h. Volatiles were evaporated in vacuo to give 1 g of the title compound as a yellow pale foam, which was used without further purification.
Workup
- customVolatiles were evaporated in vacuo
Sources & evidence
- ORD record
- ord-6389608f00bc4024aa9b779acd323f32
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07947683B2
Reaction notes
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