Water → 3-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)benzoic acid
Reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N:12]1[C:18](=[O:19])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[C:5]([O:7]C)=[O:6].[OH-].[Li+].O>C(O)C>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N:12]1[C:18](=[O:19])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[C:5]([OH:7])=[O:6]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared analogously to Example 39d from methyl 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-benzoate and lithium hydroxide in a solvent mixture of water and ethanol.
Sources & evidence
- ORD record
- ord-ec8fc6f4e79f4481a8fc75ec15905b80
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07947700B2
Reaction notes
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