Nitric Acid → 2-Amino-5-chloro-3-nitropyridine

HRID 55505

Reaction equation

HRID 55505 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][N:3]=1.[N+:9]([O-])([OH:11])=[O:10]>S(=O)(=O)(O)O>[NH2:1][C:2]1[C:7]([N+:9]([O-:11])=[O:10])=[CH:6][C:5]([Cl:8])=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 661742-Amino-5-chloropyridine

Product 1

HCID 2241682-Amino-5-chloro-3-nitropyridine

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

A procedure similar to that described in Preparation 56 was repeated, except that 25.0 g of 2-amino-5-chloropyridine, 100 ml of concentrated sulfuric acid and 12.5 ml of concentrated nitric acid were used, to give 18.5 g of the title compound, melting at 138°-139° C.

Workup

  1. customA procedure similar to that described in Preparation 56

Sources & evidence

ORD record
ord-f3a152716cff47bf9c95c59c8758e015
Source dataset
uspto-grants-1997_04
Patent number
US05624935

Linked notes

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