Hydrazine hydrate (1:1) → HCID 178481363, compound

HRID 559189

Reaction equation

HRID 559189 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:34](=[O:35])[N:33]([CH3:36])[C:11]3[N:12]([CH3:32])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19](=O)[CH2:20][C:21](=O)[CH2:22][O:23][CH:24]2[CH2:29][CH2:28][CH2:27][CH2:26][O:25]2)=[CH:15][CH:14]=4)=[CH:4][CH:3]=1.O.[NH2:38][NH2:39]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:34](=[O:35])[N:33]([CH3:36])[C:11]3[N:12]([CH3:32])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[NH:38][N:39]=[C:21]([CH2:22][O:23][CH:24]3[CH2:29][CH2:28][CH2:27][CH2:26][O:25]3)[CH:20]=2)=[CH:15][CH:14]=4)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 669983311-[3-(4-Bromophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-(tetrahydropyran-2-yloxy)butane-1,3-dione

Product 1

HCID 178481363HCID 178481363, compound

Procedure

The process is carried out as in Example 43 above, with compound A, 1-[3-(4-bromo-phenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-(tetrahydropyran-2-yloxy)butane-1,3-dione and hydrazine monohydrate.

Sources & evidence

ORD record
ord-934fd71441064accbd61e34f4f6b1e24
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Linked notes

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