a Farnesol → 3,7,11-Trimethyl-1-dodecanol

HRID 5628

Reaction equation

HRID 5628 reaction equation
[OH:1][CH2:2][CH:3]=[C:4]([CH2:6][CH2:7][CH:8]=[C:9]([CH2:11][CH2:12][CH:13]=[C:14]([CH3:16])[CH3:15])[CH3:10])[CH3:5]>C(O)C.[Pt]=O>[CH3:5][CH:4]([CH2:6][CH2:7][CH2:8][CH:9]([CH3:10])[CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:3][CH2:2][OH:1]

Participants

4

Reactant 1

HCID 3327a Farnesol

Product 1

HCID 1388243,7,11-Trimethyl-1-dodecanolYield 94.9%

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

Farnesol (200 g) was dissolved in ethanol (1000 ml), added with platinum oxide (1 g) and stirred for 24 hours at room temperature under hydrogen atmosphere. After the completion of the reaction, insoluble material was removed by filtration through a Celite layer and the filtrate was concentrated under reduced pressure to obtain 3,7,11-trimethyldodecanol (195 g).

Workup

  1. customAfter the completion of the reaction, insoluble material
  2. customwas removed by filtration through a Celite layer
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-d6aa1484224448e995eff7bbe4db6fd5
Source dataset
uspto-grants-1993_09
Patent number
US05245070

Linked notes

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