3-Chloropropionitrile → HCID 178479209, compound

HRID 569275

Reaction equation

HRID 569275 reaction equation
[S:1]([NH2:5])([NH2:4])(=[O:3])=[O:2].[Cl:6][CH2:7][CH2:8][C:9]#[N:10]>>[ClH:6].[S:1]([NH:5][C:9](=[NH:10])[CH2:8][CH2:7][Cl:6])(=[O:3])(=[O:2])[NH2:4]

Participants

3

Reactant 2

HCID 109633-ChloropropionitrileHCID 82267Sulfamide

Product 1

HCID 178479209HCID 178479209, compound

Procedure

To a suspension of 9.61 g. (0.10 mole) of sulfamide in 60 ml (68 g., 0.76 mole) of 3-chloropropionitrile dry hydrogen chloride gas is introduced under stirring at 50° to 60° C. for 5 hours. The gain in weight is about 9 to 12 g. The reaction mixture is then cooled with ice water for one hour, the product is filtered off, washed twice with acetone and dried up to steady weight.

Workup

  1. additionTo a suspension of 9.61 g
  2. filtrationthe product is filtered off
  3. washwashed twice with acetone
  4. customdried up to steady weight

Sources & evidence

ORD record
ord-92a15eb3bcfa4e919a4a19a2e213a747
Source dataset
uspto-grants-1988_03
Patent number
US04731479

Linked notes

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