HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57595Generated: October 26, 2026
Dibenzylamine → 2-(3-(Dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione
https://huagongshe.com/reaction/57595
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dibenzylamine | HCID 7656 | — |
| Reactant | N-(2,3-Epoxypropyl)phthalimide | HCID 21601 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(3-(Dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione | HCID 10408694 | 56.2% |
Reaction Steps
A mixture of 2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.06 g, 20.0 mmol) and dibenzylamine (5.0 g, 25.4 mmol) was stirred at 80° C. overnight. EtOH (50 mL) was added, and stirred at room temperature. The mixture was filtered to give white solid (4.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09434726B2 |
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| Source dataset | uspto-grants-2016_09 |
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| ORD ID | ord-b2a2f15a0b8848bb82600afc499c63de |
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| Source note | uspto-grants-2016_09 |
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