Dimethylformamide → HCID 178424083, compound

HRID 584127Notes

Reaction equation

HRID 584127 reaction equation
[C:1]1(C)[C:2]([C:7]#[N:8])=[CH:3][CH:4]=[CH:5][CH:6]=1.[NH4+].[Cl-].[N-:12]=[N+:13]=[N-:14].[Na+].[CH3:16]N(C=O)C>>[C:5]1([CH3:16])[CH:6]=[CH:1][C:2]([C:7]2[NH:8][N:14]=[N:13][N:12]=2)=[CH:3][CH:4]=1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 107212-MethylbenzonitrileHCID 25517Ammonium ChlorideHCID 33557Sodium Azide

Product 1

HCID 178424083HCID 178424083, compound

Procedure

Tolunitrile (103 mg, 1.0 mmol) was refluxed with NH4Cl (70 mg, 1.3 mmol), and NaN3 (85 mg, 1.3 mmol) in 3 mL of DMF overnight. The resulting 5-p-tolyl tetrazole was purified via RP-HPLC.

Workup

  1. customThe resulting 5-p-tolyl tetrazole was purified via RP-HPLC

Sources & evidence

ORD record
ord-a861a45610ea48e08c32a36e0d3d9260
Source dataset
uspto-grants-2005_08
Patent number
US06924284B2

Reaction notes

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