m-Chloroperbenzoic acid → N-{2-[(2-methyl-2-oxiranyl)methoxy]phenyl}acetamide

HRID 584624

Reaction equation

HRID 584624 reaction equation
[CH3:1][C:2](=[CH2:15])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:14])[CH3:13].ClC1C=CC=C(C(OO)=[O:24])C=1>>[CH3:15][C:2]1([CH2:3][O:4][C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[NH:11][C:12](=[O:14])[CH3:13])[CH2:1][O:24]1

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 13617329N-{2-[(2-Methylprop-2-en-1-yl)oxy]phenyl}acetamide

Product 1

HCID 22386946N-{2-[(2-methyl-2-oxiranyl)methoxy]phenyl}acetamideYield 65%

Procedure

The compound (0.56 g, 65%) was prepared from N-{2-[(2-methyl-2-propenyl)oxy]phenyl}acetamide (800 mg, 3.90 mmol) and m-chloroperbenzoic acid (80%, 1.10 g, 5.22 mmol) analogously to that described in Example 8 (ii).

Sources & evidence

ORD record
ord-61b5fa1065a84d4289efed705b2113f2
Source dataset
uspto-grants-2005_08
Patent number
US06927222B2

Linked notes

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