Methyl iodide → 3-Methylbenzoselenazolinone

HRID 5913

Reaction equation

HRID 5913 reaction equation
[Se:1]1(=[O:10])[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[Na].[CH3:12]I>O>[CH3:12][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[Se:1](=[O:10])[CH2:2]1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 5360545SodiumHCID 87879929Benzoselenazolinone

Product 1

HCID 867472223-Methylbenzoselenazolinone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.01 mol of benzoselenazolinone is introduced into a ground-necked round-bottomed flask containing 0.35 gram (0.015 gram-atom) of sodium dissolved in 50 l cm3 of absolute alcohol. 3.1 cm3 (0.05 mol) of methyl iodide are added dropwise and with stirring. After 12 hours, the solvent is evaporated off. The solid obtained is taken up with 30 to 40 cm3 of water and then extracted with chloroform. The chloroform phase is dried over calcium chloride and the solvent is then evaporated off under reduced pressure. The product is recrystallized in cyclohexane.

Workup

  1. customthe solvent is evaporated off
  2. customThe solid obtained
  3. extractionextracted with chloroform
  4. dry with materialThe chloroform phase is dried over calcium chloride
  5. customthe solvent is then evaporated off under reduced pressure
  6. customThe product is recrystallized in cyclohexane

Sources & evidence

ORD record
ord-22b7b4af1b9c4b7eba64bdf1c4500578
Source dataset
uspto-grants-1993_09
Patent number
US05246951

Linked notes

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