Sulfuric Acid → HCID 89767929, compound

HRID 591463

Reaction equation

HRID 591463 reaction equation
[Cl:1][CH2:2][C:3](=O)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].S(=O)(=O)(O)O.[Cl:16][C:17]1C(O)=C[CH:20]=[CH:19][C:18]=1[OH:24]>O>[Cl:16][C:17]1[C:18]([OH:24])=[CH:19][CH:20]=[C:9]2[C:8]=1[O:7][C:5](=[O:6])[CH:4]=[C:3]2[CH2:2][Cl:1]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 69484Ethyl 4-chloroacetoacetateHCID 803312-Chlororesorcinol

Product 1

HCID 89767929HCID 89767929, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To ethyl 4-chloro-3-oxobutanoate (4.91 mL) was added sulfuric acid (12.91 mL) at 0° C., then was added 2-chlorobenzene-1,3-diol (5.0 g) in several portions at 0° C. The mixture was warmed to room temperature and stirred at the same temperature for 2 h. The reaction mixture was poured into water under stirring at 0° C. The precipitate was collected by m filtration and washed with hexane to give the title compound (2.78 g).

Workup

  1. stirringunder stirring at 0° C
  2. filtrationThe precipitate was collected by m filtration
  3. washwashed with hexane

Sources & evidence

ORD record
ord-da12794c72064eccaea327c2b79c9f82
Source dataset
uspto-grants-2016_01
Patent number
US09238639B2

Linked notes

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