HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 59866Generated: October 27, 2026
Dimethylformamide dimethyl acetal → Methyl 4-[3-(dimethylamino)prop-2-enoyl]benzoate
https://huagongshe.com/reaction/59866
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Methyl 4-acetylbenzoate | HCID 137990 | — |
| Product | Methyl 4-[3-(dimethylamino)prop-2-enoyl]benzoate | HCID 10561611 | — |
Reaction Steps
A mixture of methyl 4-acetylbenzoate (5.00 g, 28.1 mmol) in DMF-DMA (38 mL, 284 mmol) was heated at 105° C. for 20 hours. The reaction was cooled, concentrated, and used crude in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09440964B2 |
|---|
| Source dataset | uspto-grants-2016_09 |
|---|
| ORD ID | ord-8ca3e56aacc74e2aae48df2c703518c5 |
|---|
| Source note | uspto-grants-2016_09 |
|---|
