1-Amino-2-propanol → 2-(5-Methyl-oxazol-2-yl)-ethylamine

Reaction equation

[CH2:1]([C:3]1[O:7][C:6]([CH2:8][CH2:9][NH2:10])=[N:5][CH:4]=1)C.NCC(O)C>>[CH3:1][C:3]1[O:7][C:6]([CH2:8][CH2:9][NH2:10])=[N:5][CH:4]=1

Participants

Reactant 2

HCID 41-Amino-2-propanol

HCID 115428012-(5-Ethyloxazol-2-yl)ethylamine

Product 1

HCID 242549802-(5-Methyl-oxazol-2-yl)-ethylamine

Procedure

This compound was made by an analogous procedure to 2-(5-ethyl-oxazol-2-yl)-ethylamine (CA1) by replacing 1-amino-2-butanol (CA1, step 1) with 1-amino-propan-2-ol.

Sources & evidence

ORD record: ord-a584a9db17df4746a53ce3008c6614d9
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07902375B2

Reaction notes

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