Iodoethane → 2-(5-methyl-2H-1,2,3,4-tetrazol-2-yl)ethan-1-amine

Reaction equation

C([N:3]1[C:7]([CH2:8]CN)=[N:6][N:5]=[N:4]1)C.[CH3:11][C:12]1[N:13]=NNN=1.C(I)C.C(OC(=O)NCCBr)(C)(C)C>>[CH3:8][C:7]1[N:6]=[N:5][N:4]([CH2:11][CH2:12][NH2:13])[N:3]=1

Participants

Reactant 4

HCID 6340Iodoethane

HCID 1381075-methyl-2H-tetrazole

HCID 4103526tert-Butyl N-(2-bromoethyl)carbamate

HCID 574668212-(1-Ethyl-1H-tetrazol-5-yl)-ethylamine

Product 1

HCID 552853532-(5-methyl-2H-1,2,3,4-tetrazol-2-yl)ethan-1-amine

Procedure

This compound is prepared by an analogous procedure to intermediate CI2 by replacing [2-(1H-Tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester in step 1 with 5-Methyl-2H-tetrazole and by replacing ethyliodide with (2-Bromo-ethyl)-carbamic acid tert-butyl ester.