Dimethylformamide dimethyl acetal → HCID 86614625, compound

Reaction equation

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])[N:3]=1.CO[CH:22](OC)[N:23]([CH3:25])[CH3:24]>>[C:8]([C:7]1[C:2]([N:1]=[CH:22][N:23]([CH3:25])[CH3:24])=[N:3][C:4]([C:10]([F:19])([F:18])[C:11]([F:16])([F:17])[C:12]([F:13])([F:14])[F:15])=[N:5][CH:6]=1)#[N:9]

Participants

Reactant 2

HCID 78373Dimethylformamide dimethyl acetal

HCID 866146264-Amino-2-(heptafluoropropyl)pyrimidine-5-carbonitrile

Product 1

HCID 86614625HCID 86614625, compound

Procedure

The title compound was prepared from the reaction of 4-Amino-2-heptafluoropropyl-pyrimidine-5-carbonitrile with N,N-dimethylformamide dimethyl acetal using the procedure from Example 156B to provide the title compound.

Sources & evidence

ORD record: ord-0e3aa929963c4efd97539c20b418731b
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07915411B2

Reaction notes

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