Hydroquinone → 4-[2-Amino-4-(4-bromo-benzyloxy)-phenoxy]-phenol

HRID 607304

Reaction equation

HRID 607304 reaction equation
[Br:1][C:2]1[CH:19]=[CH:18][C:5]([CH2:6][O:7][C:8]2[CH:13]=[CH:12][C:11](Cl)=[C:10]([N+:15]([O-])=O)[CH:9]=2)=[CH:4][CH:3]=1.[C:20]1([CH:27]=[CH:26][C:24]([OH:25])=[CH:23][CH:22]=1)[OH:21]>>[NH2:15][C:10]1[CH:9]=[C:8]([O:7][CH2:6][C:5]2[CH:18]=[CH:19][C:2]([Br:1])=[CH:3][CH:4]=2)[CH:13]=[CH:12][C:11]=1[O:21][C:20]1[CH:27]=[CH:26][C:24]([OH:25])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 785HydroquinoneHCID 574698834-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene

Product 1

HCID 668085674-[2-Amino-4-(4-bromo-benzyloxy)-phenoxy]-phenol

Procedure

4-(4-Bromo-benzyloxy)-1-chloro-2-nitro-benzene (from Example 16A) was reacted with hydroquinone according to the procedure from Example 39A and reduced according to the procedure from Example 39B to provide the title product.

Sources & evidence

ORD record
ord-70139d9f0f56406b84ad765ca809e475
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Linked notes

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