Hydrochloric Acid → 6-(4-Phenethylbenzoyl)-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine hydrochloride
Reaction equation
[CH2:1]([C:9]1[CH:31]=[CH:30][C:12]([C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]4[CH2:29][CH2:28][CH2:27][CH2:26]4)[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:11][CH:10]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[ClH:32]>CO>[ClH:32].[CH2:1]([C:9]1[CH:31]=[CH:30][C:12]([C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:11][CH:10]=1)[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
6-(4-Phenethylbenzoyl)-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine 1.004 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.