1,2-Benzenedicarboxylic acid, 4-nitro-, 1,2-dimethyl ester → HCID 19595674, compound

HRID 612582

Reaction equation

HRID 612582 reaction equation
[N+]([C:4]1[CH:5]=[C:6]([C:14]([O:16][CH3:17])=[O:15])[C:7](=[CH:12][CH:13]=1)[C:8]([O:10][CH3:11])=[O:9])([O-])=O.[Na].[OH:19][C:20]1[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=1>CN(C=O)C>[N:22]1[CH:23]=[CH:24][CH:25]=[C:20]([O:19][C:4]2[CH:5]=[C:6]([C:14]([O:16][CH3:17])=[O:15])[C:7](=[CH:12][CH:13]=2)[C:8]([O:10][CH3:11])=[O:9])[CH:21]=1

Participants

4

Reactant 2

HCID 691191,2-Benzenedicarboxylic acid, 4-nitro-, 1,2-dimethyl esterHCID 6679647152536-09-1

Product 1

HCID 19595674HCID 19595674, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Dimethyl 4-nitrophthalate was reacted in DMF with 3-hydroxypyridine sodium salt in analogy to a process known from the literature (J. Org. Chem. Vol. 42, No. 21, 1977, 3419-3425) to give dimethyl 4-(3-pyridyloxy)phthalate. After standard working up and chromatography using hexane/EA, the diester was isolated as a yellowish oil.

Sources & evidence

ORD record
ord-b39331cc2a22480bb61db833342b2693
Source dataset
uspto-grants-1999_12
Patent number
US06005010

Linked notes

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