Ethanolamine → N-(2-hydroxyethyl)lactamide

HRID 614086

Reaction equation

HRID 614086 reaction equation
[C:1]([O:6]CC)(=O)[CH:2]([CH3:4])[OH:3].[CH2:9]([CH2:11][NH2:12])[OH:10]>C(O)C>[OH:10][CH2:9][CH2:11][NH:12][C:1](=[O:6])[CH:2]([CH3:4])[OH:3]

Participants

4

Reactant 2

HCID 700EthanolamineHCID 7344Ethyl Lactate

Product 1

HCID 95457N-(2-hydroxyethyl)lactamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
60 °C

Procedure

A mixture of 70.8 gm (0.6 mole) of ethyl lactate and 36.6 gm (0.6 mole) of ethanolamine were stirred together at 60° C. for 16 hours, and the ethanol formed was subsequently distilled off under reduced pressure. 71 gm (89% of theory) of light yellow, viscous N-(2-hydroxyethyl)-lactic acid amide of refractive index (nD20) 1.4850 were obtained.

Workup

  1. distillationwas subsequently distilled off under reduced pressure

Sources & evidence

ORD record
ord-de0158ec03774a6aa1076a2cdc2f7e1e
Source dataset
uspto-grants-1979_03
Patent number
US04143159

Linked notes

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