m-Chloroperbenzoic acid → HCID 178504633, compound
Reaction equation
[NH2:1][C:2]1[NH:3][S:4](=[O:13])(=[O:12])[N:5]=[C:6]([CH2:8][CH2:9][S:10][CH3:11])[N:7]=1.ClC1C=CC=C(C(OO)=[O:22])C=1>CO.C(Cl)(Cl)Cl>[NH2:1][C:2]1[NH:3][S:4](=[O:13])(=[O:12])[N:5]=[C:6]([CH2:8][CH2:9][S:10]([CH3:11])=[O:22])[N:7]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
To a solution of 3-amino-5-[2-(methylthio)ethyl]-1,2,4,6-thiatriazine-1,1-dioxide (1.22 gm, 5.5 mmol) in warm methanol (20 ml) there was added dropwise a solution of 80% pure m-chloroperbenzoic acid (1.2 gm, 5.6 mmol) in chloroform (20 ml). The product crystallized from solution during the addition and was collected by filtration and washed with diethyl ether to give 1.27 gm of pure product, m.p. 180°-182° C.
Workup
- customThe product crystallized from solution during the addition
- filtrationwas collected by filtration
- washwashed with diethyl ether
Sources & evidence
- ORD record
- ord-bf78132cdaa44872836e427e004f87b4
- Source dataset
- uspto-grants-1985_02
- Patent number
- US04497810
Reaction notes
Loading…