4-Piperidinol, 1-methyl- → HCID 66834205, compound

HRID 61708

Reaction equation

HRID 61708 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:22])([CH3:21])[C:6]=2[CH:23]=1.[CH3:24][N:25]1[CH2:30][CH2:29][CH:28](O)[CH2:27][CH2:26]1>>[CH3:22][C:7]1([CH3:21])[C:8]2[NH:9][C:10]3[C:15](=[CH:14][CH:13]=[C:12]([C:19]#[N:20])[CH:11]=3)[C:16]=2[C:17](=[O:18])[C:5]2[CH:4]=[CH:3][C:2]([O:1][CH:28]3[CH2:29][CH2:30][N:25]([CH3:24])[CH2:26][CH2:27]3)=[CH:23][C:6]1=2

Participants

3

Reactant 2

HCID 660484-Piperidinol, 1-methyl-HCID 668338618-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Product 1

HCID 66834205HCID 66834205, compound

Procedure

Under the same conditions as the method for synthesizing Compound A7-1, the title compound was prepared from Compound A6 and 1-methylpiperidin-4-ol.

Workup

  1. customUnder the same conditions as the method for synthesizing Compound A7-1

Sources & evidence

ORD record
ord-54f8b68cae3c447581f531cb4dfd1c7c
Source dataset
uspto-grants-2016_09
Patent number
US09440922B2

Linked notes

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