Hydrochloric Acid → Ethyl 3-methylbenzimidate hydrochloride

HRID 617635

Reaction equation

HRID 617635 reaction equation
[C:1]1([CH3:9])[CH:6]=[CH:5][CH:4]=[C:3]([C:7]#[N:8])[CH:2]=1.[ClH:10].[CH2:11]([OH:13])[CH3:12]>>[ClH:10].[CH3:9][C:1]1[CH:2]=[C:3]([CH:4]=[CH:5][CH:6]=1)[C:7](=[NH:8])[O:13][CH2:11][CH3:12]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 121043-Tolunitrile

Product 1

HCID 21938086Ethyl 3-methylbenzimidate hydrochloride

Procedure

Ethyl 3-methylbenzimidate hydrochloride was synthesized in the same manner as in Reference Example 2. That is, m-tolunitrile (25.2 g, 0.215 mol) was treated with hydrogen chloride in ethanol (250 mL) to give 41.7 g (97%) of the target compound as colorless crystals.

Sources & evidence

ORD record
ord-472e9956c224470ca9bd5bd552bcd52d
Source dataset
uspto-grants-1999_09
Patent number
US05948785

Linked notes

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