Benzaldehyde → 5-Benzylamino-2-fluoro-N-isopropyl-benzamide

Reaction equation

[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([F:14])=[C:6]([CH:13]=1)[C:7]([NH:9][CH:10]([CH3:12])[CH3:11])=[O:8].[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([F:14])=[C:6]([CH:13]=1)[C:7]([NH:9][CH:10]([CH3:11])[CH3:12])=[O:8])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 43510674HCID 43510674, compound

Product 1

HCID 673103385-Benzylamino-2-fluoro-N-isopropyl-benzamide

Procedure

5-Benzylamino-2-fluoro-N-isopropyl-benzamide was synthesized from 5-amino-2-fluoro-N-isopropyl-benzamide and benzaldehyde according to the method described in Example 1

Sources & evidence

ORD record: ord-ddabd36082674bd2b310a2a6d69686af
Source dataset: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09447033B2

Reaction notes

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