3-Bromo-1,1,1-trifluoropropane → HCID 62033693, compound

HRID 62870

Reaction equation

HRID 62870 reaction equation
[SH:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Br[CH2:12][CH2:13][C:14]([F:17])([F:16])[F:15]>>[F:15][C:14]([F:17])([F:16])[CH2:13][CH2:12][S:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 27251143-Bromo-1,1,1-trifluoropropaneHCID 178524460HCID 178524460, compound

Product 1

HCID 62033693HCID 62033693, compoundYield 10%

Procedure

2-Mercapto-nicotinic acid (1 g, 6.4 mmol) and 3-bromo-1,1,1-trifluoropropane were reacted in the same manner as in Step A of Preparation Example 10 to obtain the title compound (0.16 g, 10%).

Sources & evidence

ORD record
ord-1c1801a6c51a4b27bf71e7c919c5b737
Source dataset
uspto-grants-2016_09
Patent number
US09447044B2

Linked notes

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