4-Bromobenzaldehyde → 4-Propylbenzaldehyde

HRID 629146

Reaction equation

HRID 629146 reaction equation
Br[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[CH2:10](B(O)O)[CH2:11][CH3:12]>>[CH2:10]([C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)[CH2:11][CH3:12]

Participants

3

Procedure

The compound was synthesized as in Example 3.1 using 4-bromobenzaldehyde (250 mg, 1.35 mmol) in place of 5-bromo-2-formylfuran and propylboronic acid (196 mg, 2.23 mmol) in place of hexylboronic acid to give 4-propylbenzaldehyde (58 mg, 29%). Used without further characterization.

Sources & evidence

ORD record
ord-9a56ff601438472b991f1a7ac6391bd9
Source dataset
uspto-grants-2016_04
Patent number
US09315495B2

Linked notes

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