Methyl 5-bromo-2-hydroxy-4-methylbenzoate → Methyl 5-((6-chloropyridin-3-yl)methyl)-2-hydroxy-4-methylbenzoate
Reaction equation
Br[C:2]1[C:3]([CH3:13])=[CH:4][C:5]([OH:12])=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[Cl-].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][Zn+])=[CH:18][N:17]=1.C1COCC1>C1COCC1.CC(C)([P](C(C)(C)C)([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)C(C)(C)C)C>[Cl:15][C:16]1[N:17]=[CH:18][C:19]([CH2:22][C:2]2[C:3]([CH3:13])=[CH:4][C:5]([OH:12])=[C:6]([CH:11]=2)[C:7]([O:9][CH3:10])=[O:8])=[CH:20][CH:21]=1Participants
5
