4-Chloro-6-methoxyquinazolin-7-yl acetate → N-(3-fluorophenyl)-2-{4-[(7-hydroxy-6-methoxyquinazolin-4-yl)amino]-1H-pyrazol-1-yl}acetamide
Reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][N:5]([CH2:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[CH:12]=2)=[O:9])[CH:6]=1.[C:18]([O:21][C:22]1[CH:31]=[C:30]2[C:25]([C:26](Cl)=[N:27][CH:28]=[N:29]2)=[CH:24][C:23]=1[O:33][CH3:34])(=[O:20])[CH3:19]>CC(N(C)C)=O.C(OCC)C>[C:18]([O:21][C:22]1[CH:31]=[C:30]2[C:25]([C:26]([NH:1][C:2]3[CH:3]=[N:4][N:5]([CH2:7][C:8]([NH:10][C:11]4[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[CH:12]=4)=[O:9])[CH:6]=3)=[N:27][CH:28]=[N:29]2)=[CH:24][C:23]=1[O:33][CH3:34])(=[O:20])[CH3:19].[F:17][C:13]1[CH:12]=[C:11]([NH:10][C:8](=[O:9])[CH2:7][N:5]2[CH:6]=[C:2]([NH:1][C:26]3[C:25]4[C:30](=[CH:31][C:22]([OH:21])=[C:23]([O:33][CH3:34])[CH:24]=4)[N:29]=[CH:28][N:27]=3)[CH:3]=[N:4]2)[CH:16]=[CH:15][CH:14]=1Participants
6
