Methylparaben → Methyl 4-(pyridin-2-ylmethoxy)benzoate

HRID 642175

Reaction equation

[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.Br.Br[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1>>[CH3:9][O:8][C:6](=[O:7])[C:5]1[CH:4]=[CH:3][C:2]([O:1][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)=[CH:11][CH:10]=1

Participants

Reactant 2

HCID 7456Methylparaben

HCID 27347202-(Bromomethyl)pyridine hydrobromide

Product 1

HCID 2416604Methyl 4-(pyridin-2-ylmethoxy)benzoate

Procedure

The title compound is prepared in a manner substantially analogous to Procedure E from methyl 4-hydroxybenzoate and 2-(bromomethyl)pyridine hydrobromide.

Sources & evidence

ORD record: ord-97cc04f05aaf4da39b2c151e911a74f6
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07696234B2

Linked notes

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