Triethylamine → HCID 19020431, compound

Reaction equation

[S:1]1[C:7]2[CH:8]=[CH:9][S:10][C:6]=2[C:5](=[S:11])[NH:4][CH2:3][CH2:2]1.S(NN=[C:24]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:25](Cl)=[O:26])(C1C=CC(C)=CC=1)(=O)=[O:13].C(N(CC)CC)C>C(Cl)Cl>[OH-:13].[OH:26][C:25]1[N+:4]2[CH2:3][CH2:2][S:1][C:7]3[CH:8]=[CH:9][S:10][C:6]=3[C:5]=2[S:11][C:24]=1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

Procedure

0.6 g of 3,4-dihydro-thieno[2,3-f][1,4]thiazepine-5(2H)-thione and 1.0 g of α-(tosylhydrazono)phenylacetyl chloride were stirred for a long time in 50 ml of methylene chloride at room temperature and in the presence of 0.84 ml of triethylamine. The solvent was removed in vacuo and the residue was chromatographed on silica gel. There was obtained 5,6-dihydro-8-hydroxy-9-phenyl-thiazolo[3,2-d]thieno[2,3-f][1,4]thiazepinium hydroxide (internal salt) of m.p. 190°-195°.