Benzyl Bromide → HCID 14155410, compound

Reaction equation

[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[CH2:11](Br)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[NH2:1])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 14155407(2-Amino-3-chlorophenyl)methanol

Product 1

HCID 14155410HCID 14155410, compound

Procedure

This material was prepared from 2-amino-3-chlorobenzyl alcohol and benzyl bromide by the general procedure outlined in Example 82. The product was purified by Kugelrohr distillation to yield an oil, bp 118°-125° C. (0.1 mm). The product was characterized by IR and 1H NMR spectroscopy.

Workup

distillationThe product was purified by Kugelrohr distillation
customto yield an oil, bp 118°-125° C. (0.1 mm)

Sources & evidence

ORD record: ord-97103f70acf547178c555de40e997bd7
Source dataset: uspto-grants-1988_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04740233

Reaction notes

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