Calcium Carbonate → calcium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylate

HRID 65087

Reaction equation

HRID 65087 reaction equation
C(=O)([O-])[O-].[Ca+2:5].[Cl-].[NH4+].[Ca].[C:9]([C:17]1[N:21]2[CH2:22][CH2:23][CH:24]([C:25]([O-:27])=[O:26])[C:20]2=[CH:19][C:18]=1[S:28][CH3:29])(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[K+]>Cl.O>[C:9]([C:17]1[N:21]2[CH2:22][CH2:23][CH:24]([C:25]([O-:27])=[O:26])[C:20]2=[CH:19][C:18]=1[S:28][CH3:29])(=[O:16])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1.[Ca+2:5].[C:9]([C:17]1[N:21]2[CH2:22][CH2:23][CH:24]([C:25]([O-:27])=[O:26])[C:20]2=[CH:19][C:18]=1[S:28][CH3:29])(=[O:16])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

7

Reactant 4

HCID 10112Calcium Carbonate2×HCID 25517Ammonium ChlorideHCID 5460341CalciumHCID 23711367potassium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate

Product 1

HCID 20235121calcium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylate

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

A solution of 40 mg of calcium carbonate dissolved in the minimum amount of 1N hydrochloric acid necessary to effect solution of the calcium carbonate, is buffered with 100 mg of solid ammonium chloride, followed by the further addition of 5 ml of water. The thus obtained buffered calcium solution is then added to the solution of potassium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate and the precipitate which forms is collected by filtration, washed with water and air dried to yield calcium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylate.

Workup

  1. customThe thus obtained
  2. filtrationthe precipitate which forms is collected by filtration
  3. washwashed with water and air
  4. customdried

Sources & evidence

ORD record
ord-cb308c3f45c84795a41387d140f54724
Source dataset
uspto-grants-1986_09
Patent number
US04612325

Linked notes

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