Sodium Carbonate → 6-(2-Chlorophenyl)-3-(4-oxopiperidino)-1,2,4-triazine

HRID 65203

Reaction equation

HRID 65203 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[Cl:14])=[CH:6][N:7]=1.Cl.O.[NH:17]1[CH2:22][CH2:21][C:20](=[O:23])[CH2:19][CH2:18]1.C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[Cl:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[C:5]1[N:4]=[N:3][C:2]([N:17]2[CH2:22][CH2:21][C:20](=[O:23])[CH2:19][CH2:18]2)=[N:7][CH:6]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 2723901PiperonylamineHCID 125812883-Chloro-6-(o-chlorophenyl)-1,2,4-triazine

Product 1

HCID 136055276-(2-Chlorophenyl)-3-(4-oxopiperidino)-1,2,4-triazine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.5 g of 3-chloro-6-(2-chlorophenyl)-1,2,4-triazine, 3.05 g of piperidin-4-one monohydrate hydrochloride and 3.1 g of sodium carbonate are heated under reflux in 100 ml of ethanol for 4 hours.

Sources & evidence

ORD record
ord-bde75dd99363429981065e3c265be9d8
Source dataset
uspto-grants-1986_09
Patent number
US04613603

Linked notes

Loading…